|
1 / 1
|
DeCS
|
|
 |
|
Descriptor English:
|
|
Neprilysin
|
|
Descriptor Spanish:
|
|
Neprilisina
|
|
Descriptor Portuguese:
|
|
Neprilisina
|
|
Synonyms English:
|
|
CALLA Antigen
Enkephalin Dipeptidyl Carboxypeptidase
Enkephalinase
Kidney-Brush-Border Neutral Proteinase
Antigens, CD10
Antigens, Leukemia, Common Acute Lymphoblastic
Common Acute Lymphoblastic Leukemia Antigens
CD10 Antigens
Endopeptidase-24.11
Membrane Metallo-Endopeptidase
|
|
Tree Number:
|
|
D08.811.277.656.300.480.600
D08.811.277.656.675.374.600
D23.050.285.550
D23.050.301.264.035.550
D23.101.100.110.550
D23.101.840.500
|
|
Definition English:
|
|
Enzyme that is a major constituent of kidney brush-border membranes and is also present to a lesser degree in the brain and other tissues. It preferentially catalyzes cleavage at the amino group of hydrophobic residues of the B-chain of insulin as well as opioid peptides and other biologically active peptides. The enzyme is inhibited primarily by EDTA, phosphoramidon, and thiorphan and is reactivated by zinc. Neprilysin is identical to common acute lymphoblastic leukemia antigen (CALLA Antigen), an important marker in the diagnosis of human acute lymphocytic leukemia. There is no relationship with CALLA PLANT. |
|
History Note English:
|
|
97; was MEMBRANE METALLO-ENDOPEPTIDASE 1989-96; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGENS was COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGENS (NM) 1983-92
|
|
Allowable Qualifiers English:
|
|
|
|
Record Number:
|
|
23757
|
|
Unique Identifier:
|
|
D015260
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS SciELO LILACS LIS
|